Table 2 The effects of the crude ES and fractionated ES at 300 μg/ml on lesion size (mean ± SD) of Leishmania-infected mice versus positive and negative controls at different time points post-infection

7.6 ± 2.61

6.6 ± 2.50

4.8 ± 2.59*

3.8 ± 2.05*

2.6 ± 1.82*

7.4 ± 2.07

7.2 ± 1.92

6.4 ± 1.82

5.8 ± 1.92*

5 ± 2.35*

6.6 ± 2.05

6.4 ± 2.30

5.8 ± 2.77

5.4 ± 2.30*

5.2 ± 2.28*

6.8 ± 1.72

6.4 ± 2.15

4.8 ± 1.72*

3.6 ± 1.74*

2.2 ± 1.33*

7.4 ± 1.82

8.4 ± 1.80

9.4 ± 1.86

10.6 ± 1.72

12 ± 1.87

7 ± 2

8.2 ± 1.92

9.6 ± 2.30

11.2 ± 2.77

12.8 ± 2.86