Treatment | Dosage (μg/ml) | Infected cells (%) | Viability of amastigotes (%) | Parasite load | Survival index |
---|---|---|---|---|---|
Control | 0 | 85.37 ± 3.58 | 100 ± 0.00 | 3.19 ± 0.01 | 270.9 ± 1.15 |
Crude ES | 150 | 41.66 ± 1.28* | 30.27 ± 1.93* | 1.97 ± 0.02* | 82.23 ± 2.35* |
 | 300 | 32.00 ± 2.43* | 20.58 ± 2.74* | 1.75 ± 0.05* | 53.72 ± 2.44* |
> 10-kDa ES | 150 | 58.33 ± 2.75 | 49.90 ± 2.71* | 2.28 ± 0.03 | 132.99 ± 2.01* |
 | 300 | 51.00 ± 1.55* | 39.46 ± 3.42* | 2.10 ± 0.01* | 107.33 ± 2.51* |
< 10-kDa ES | 150 | 62.66 ± 2.38 | 59.93 ± 2.86* | 2.60 ± 0.10 | 162.73 ± 2.10* |
 | 300 | 55.00 ± 3.10* | 49.02 ± 3.53* | 2.42 ± 0.00* | 133.21 ± 2.38* |
Glucantime | 50 | 39.66 ± 2.08* | 28.54 ± 0.56* | 1.96 ± 0.07* | 77.67 ± 1.53* |
 | 100 | 30.85 ± 1.53* | 15.51 ± 1.12* | 1.68 ± 0.02* | 51.01 ± 2.01* |