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Table 3 Analysis of calmodulin (CaM) and Ca2+/calmodulin-dependent protein kinase II (CaMKII) protein levels in E. multilocularis-infected mice after oral administration of Vepm for 4 months by enzyme-linked immunosorbent assay

From: Anti-echinococcal effect of verapamil involving the regulation of the calcium/calmodulin-dependent protein kinase II response in vitro and in a murine infection model

Index

Sample

Uninfected group

Infected groupa

Vepm groupb

CaM (μg/ml)

Serum

13.81 ± 1.65

22.25 ± 5.55*

8.13 ± 1.26*

Liver

3.42 ± 0.27

6.06 ± 1.83*

1.60 ± 0.68*

Cysts

NA

2.36 ± 0.87

1.68 ± 0.10

CaMKII (ng/ml)

Serum

5.88 ± 0.99

22.87 ± 4.23*

5.13 ± 1.74*

Liver

2.00 ± 0.61

4.25 ± 1.84*

1.97 ± 0.56*

Cysts

NA

2.65 ± 1.24

1.79 ± 0.36

  1. *P < 0.05
  2. aInfected group vs. the uninfected group
  3. bVepm group vs. the infected group
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Parasites & Vectors

ISSN: 1756-3305

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