Table 1 Parameter values for Schistosoma haematobium used in making model predictions of MDA impact (some directly estimated from age-intensity or prevalence profiles and some derived from the literature).
Parameter | Value | Source |
|---|---|---|
Population size | 500 | – |
Fecundity | 3.6 eggs/female/sample | |
Transmission intensity | R0 = 2.5 | Fitted |
Level of aggregation of parasites in host population | Negative binomial, k = 0.24 | [28] |
Adult worm life expectancy | 4 years | |
Praziquantel drug efficacy | 99% | |
Age specific contact rates (\({\varvec{\beta}}\)) for the first dataset [25] | For 0–4, 5–11,12–20, 21+ years of age: 0.17, 1, 0.11, 0.035 | Fitted |
Contribution to the reservoir by contact age group (\({\varvec{\rho}}\)) for the first dataset [25] | For 0–4, 5–11,12–20, 21+ years of age: 0.17, 1, 0.11, 0.035 | Fitted |
Age specific contact rates (\({\varvec{\beta}}\)) for the second dataset [18] | For 0–4, 5–11, 12+ years of age: 0.0035, 1, 0.0037 | Fitted |
Contribution to the reservoir by contact age group (\({\varvec{\rho}}\)) for the second dataset [18] | For 0–4, 5–11, 12+ years of age: 0.0035, 1, 0.0037 | Fitted |
Prevalence of infection | Percentage of population having > 0 eggs/10 ml | – |
Heavy-intensity infection prevalence | Percentage of population having ≥ 50 eggs/10 ml | |
Human demography | Based on Kenya’s demographic profile | – |