Year | 2001 | 2002 | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Day/Month | 23/04 | 27/04 | 14/05 | 29/06 | 28/08 | 09/02 | 07/03 | 21/06 | 03/09 | 23/09 | 25/09 | 18/10 | |
Hematology (reference) | |||||||||||||
 Erythrocytes (> 5.5/pl) | 7.05 | 6.21 | 6.78 | 7.84 | 7.56 | 7.11 |  | 6.75 | 7.15 | 5.72 | 6.33 | 6.46 | |
 Hemoglobin (> 8.8 mmol/l) | 10.66 | 9.42 | 10.23 | 11.90 | 10.97 | 10.60 |  | 10.66 | 11.04 | 8.37 | 9.05 | 9.61 | |
 HT (> 42%) | 51 | 46 | 48 | 61 | 56 | 54 |  | 49 | 52 | 39 | 43 | 50 | |
 MCV (65.5–75.5 fl) | 71.70 | 73.60 | 71.10 | 77.30 | 73.90 | 75.40 |  | 73.20 | 72.50 | 67.80 | 68.20 | 78.10 | |
 MCH (0.90–1.55 pmol) | 1.46 | 1.47 | 1.46 | 1.47 | 1.40 | 1.45 |  | 1.53 | 1.49 | 1.42 | 1.39 | 1.45 | |
 MCHC (20.9–22.3 mmol/l) | 21.08 | 20.58 | 21.2 | 19.59 | 19.59 | 19.78 |  | 21.58 | 21.20 | 21.64 | 21.02 | 19.10 | |
 Thrombocytes (150–400/nl) | 9 | 50 | 131 | 23 | 17 | 192 |  | 216 | 180 | 50 | 187 | 206 | |
 Leukocytes (5.9–13.8/nl) | 11.4 | 11.6 | 14.5 | 8.4 | 8.9 | 7.9 |  | 7.9 | 8.2 | 7.8 | 6.8 | 8.5 | |
 Neutrophils (55–75%) | 73 | 79 | 71 | 55 | 67 | 65 |  | 66 | 61 | 78 | 42 | 73 | |
 Lymphocytes (13–30%) | 16 | 18 | 16 | 35 | 22 | 27 |  | 23 | 33 | 9 | 52 | 21 | |
 Monocytes (< 5%) | 8 | 1 | 4 | 9 | 5 | 6 |  | 2 | 5 | 9 | 4 | 5 | |
 Eosinophils (< 4%) | 2 | 1 | 6 | 1 | 4 | 1 |  | 9 | 1 | 0 | 2 | 1 | |
 Basophils (< 1%) | 0 |  | 0 | 0 | 0 | 0 |  | 0 | 0 | 0 | 0 | 0 | |
 Staphylococcus (< 4%) | 1 | 1 | 3 | 0 | 2 | 1 |  | 0 | 0 | 4 | 0 | 0 | |
Serology | |||||||||||||
 Anaplasma | Immunoblot | neg2 | neg2 | neg2 | neg3 | neg3 | neg3 |  | neg3 | neg3 | pos 3 | pos 3 | pos 3 |
IFT | pos 1 | pos 1 | neg1 | Â | Â | Â | Â | Â | Â | Â | Â | Â | |
Snap test | Â | neg | neg | neg | neg | Â | Â | neg | neg | Â | pos | neg | |
 Borrelia | WHC-titer |  | 80 | 40 |  |  |  |  |  |  |  |  |  |
C6 Snap test | neg | neg | neg | neg | neg | Â | Â | neg | neg | Â | neg | neg | |
Coagulation test | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | normal | |
 Microscopy (morulae) | pos | neg | neg | neg | neg | neg |  |  | neg | pos | neg | neg | |
 PCR - DNA | pos 2,4 | neg2 | pos 2 | neg2 | neg3 | neg3 |  | neg3 | neg3,4 | pos 1,3,4 | pos 3 | neg1,3 | |
 RLB | A. phago variant 1 | pos 2 |  | neg |  |  |  |  |  |  | pos 3 | neg |  |
A. phago variant 2 | neg | Â | neg | Â | Â | Â | Â | Â | Â | neg | neg | Â | |
A. phago variant 3 | neg | Â | neg | Â | Â | Â | Â | Â | Â | neg | neg | Â | |
A. phago variant 4 | neg | Â | pos 2 | Â | Â | Â | Â | Â | Â | pos 3 | neg | Â | |
E. equi | neg | Â | neg | Â | Â | Â | Â | Â | Â | Â | Â | Â | |
HGE agent | neg | Â | neg | Â | Â | Â | Â | Â | Â | pos 3 | pos 3 | Â | |
 Clinics | |||||||||||||
 | Body temperature | 38.8 | 38.4 | 38.4 | 38.5 | 38.2 | 38.3 | 38.3 | 38.2 |  | 39.6 |  | 38.5 |
Bleeding | ecchm | resolv | no | no | no | no | no | no | no | no | no | no | |
Other | listless, lymphaden. R popliteus | pseudolac | Â | lame | myositis, lays, pseudolac, lameness | pseudolac | dyspneu | cough | |||||
Therapy | Â | doxy | Â | Â | doxy | Â | doxy | doxy | Â | Â | doxy | amox/clv | |
Ticks on dog | yes | Â | Â | Â | Â | yes | Â | yes | yes | yes | Â | yes |