Fig. 3
Gene ontology and expression profiles of differentially-expressed transcripts in TBEV-infected IDE8 and IRE/CTVM19 cells. Each individual transcript of IDE8 (a) and IRE/CTVM19 (b) differentially expressed on days 2 (2d) and 6 (6d) p.i. was assigned to a biological process group according to its regulation status (up or down). Biological process (ontology) groups were assigned using information available on UniProt/Swiss-Prot databases, and were then manually curated according to gene function published in the literature. c Differentially-expressed transcripts in IDE8 and IRE/CTVM19 and their levels of differential expression on days 2 (2d) and 6 (6d) p.i. are depicted in the heatmap. Green = up-regulation; red = down-regulation; black = no change. Numbers on the colour key indicate the log2-fold change in differential expression