Table 1 Model parameters

Mosquito density (ratio female mosquitoes/humans)

m

Assumed value within published range

Human feeding rate, bites per mosquito per day

a

Monthly estimations from fitting cohort data; values within published range

Susceptibility of an individual to infection after being bitten by an infectious mosquito

b

Estimation using cohort and published data

Mosquito susceptibility to infection after biting an infectious individual

c

Published data

Duration of human latent period for Pf* in d]’ cays (l = l ₁ + l ₂ )

l

Published data

Duration from sporozoite inoculation to development of blood asexual parasites in days

l ₁

Published data

Duration from asexual blood stage infection to development of gametocytes in days

l ₂

Published data

Duration of mosquito latent period in days

n

Published data

Daily human mortality rate

h

Published data

Daily mosquito mortality rate

g

Published data

Fraction of symptomatic infections

y

Cohort data

Treatment effectiveness

ε

Published data

Duration of infectious period in treated humans with ACT (in days)

r ₁

Published data

Duration of infectious period in untreated humans in days (r ₂ = r _2a + r _2b )

r ₂

Published data

Duration of presence of blood asexual parasites in untreated humans in days

r _2a

Published data

Duration of infectious period in untreated humans after clearance of blood asexual parasites in days

r _2b

Published data

Coverage of FSAT

Δ

Assumption

Duration of FSAT in days

v

Assumption

Sensitivity of microscopy for detecting Pf* asexual stages

s _1a

Published data

Sensitivity of microscopy for detecting Pf*gametocytes

s _1g

Published data

Sensitivity of highly sensitive diagnostic tests for detecting asexual stages

s _2a

Assumption

Sensitivity of highly sensitive diagnostic tests for detecting gametocytes

s _2g

Assumption