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Table 2 Cytological and histopathological patterns suggestive of canine L. infantum infection found in organs or body fluids.

From: LeishVet guidelines for the practical management of canine leishmaniosis

Pathological findings in organs or body fluids

✔ Macrophagic inflammation (granulomatous)

✔ Neutrophilic-macrophagic inflammation (pyogranulomatous)

✔ Lymphoplasmacytic inflammation

✔ Reactive hyperplasia in lymphoid organs

✔ No evidence or variable numbers of intracellular or extracellular Leishmania amastigotes