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Table 1 IC50 values of tribendimidine and praziquantel against newly excysted metacercariae and adult Opisthorchis felineus worms

From: A study of tribendimidine effects in vitro and in vivo on the liver fluke Opisthorchis felineus

Compound

NEM

Adults

Tribendimidine (TBN) (μM)

0.23 ± 0.059

0.19 ± 0.1

Praziquantel (PZQ) (μM)

0.98 ± 0.18

0.47 ± 0.05

  1. For calculation of the half-maximal inhibitory concentration (IC50), we tested the following concentrations of compounds: 0.001, 0.01, 0.1, 1, 10 and 100 μM. Data are presented as IC50 values ± standard error (R package drc 3.0-1)
  2. Abbreviation: NEM, newly excysted metacercariae