Day of study | Arithmetic mean ± SD | Geometric mean | t-value | P-value | Efficacy (%)a | ||
---|---|---|---|---|---|---|---|
Control | Lotilaner | Control | Lotilaner | ||||
3 | 22.3 ± 3.5 | 0.0 ± 0.0 | 22.0 | 0 | † | † | 100 |
17 | 24.1 ± 1.3 | 0.0 ± 0.0 | 24.1 | 0 | † | † | 100 |
31 | 25.9 ± 2.0 | 0.0 ± 0.0 | 25.8 | 0 | † | † | 100 |
45 | 23.4 ± 4.3 | 0.0 ± 0.0 | 23.0 | 0 | † | † | 100 |
59 | 24.6 ± 2.3 | 0.0 ± 0.0 | 24.5 | 0 | † | † | 100 |
73 | 23.6 ± 2.7 | 0.8 ± 2.1 | 23.5 | 0.3 | t(266)=8.5 | <0.0001 | 98.8 |
80 | 26.1 ± 1.6 | 2.9 ± 8.1 | 26.1 | 0.5 | t(266)=11.0 | <0.0001 | 98.1 |
87 | 26.3 ± 3.9 | 4.1 ± 8.4 | 26.0 | 1.2 | t(266)=11.3 | <0.0001 | 95.3 |