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Table 5 Relative weight of gene interactions in T. cruzi-infected HPE

From: Host-parasite interaction: changes in human placental gene expression induced by Trypanosoma cruzi

Network group

2 h/105 Up

2 h/105 Down

2 h/106 Up

2 h/106 Down

24 h/105 Up

24 h/105 Down

24 h/106 Up

24 h/106 Down

Co-expression

72

61

64

42

75

66

75

75

Co-localization

13

7

18

9

11

6

14

3

Physical interactions

7

14

11

31

6

17

6

9

Genetic interactions

4

0

2

4

3

0

0

1

Shared protein domains

0

1

1

3

0

1

1

0

Pathway

0

1

1

3

0

0

1

7

Others

4

16

3

8

5

10

3

5

  1. Abbreviations: Up, upregulated; Down, downregulated; H, hours of HPE incubation with the parasite; 105, challenge with 105 parasites/ml; 106, challenge with 106 parasites/ml