Fig. 6From: Physiological and immunological responses to Culicoides sonorensis blood-feeding: a murine modelDose-dependent mast cell degranulation in response to Culicoides sonorensis salivary proteins. Connective tissue mast cells (CTMCs) or 3T6 fibroblast cells were exposed to C. sonorensis salivary proteins (100–1000 ng/ml) or the potent chemical mast cell activator compound 48/80 for 1 h after which β-hexosaminidase release was quantified. (***P < 0.001, ****P < 0.0001; two-way ANOVA with Sidak’s multiple comparisons test)Back to article page