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Table 1 Proteins selected as candidate protective antigens

From: A reverse vaccinology approach to the identification and characterization of Ctenocephalides felis candidate protective antigens for the control of cat flea infestations

Sequence ID

Uniprot accession No.

Description

Transcript identified

Protein levels (PSMs)

F1

C6H0K8

C. felis arginine kinase 1 (argk1)

Yes

43b

F2a

Q27766

C. felis sodium/potassium-transporting ATPase subunit alpha (Na+/K+ ATPase)

Yes

3b; 62c

F3

Q8IS50

C. felis serpin 4

No

4b

F4

Q8MZR6

C. felis juvenile hormone epoxide hydrolase 1 (JHEH I)

Yes

2c

F5

Q7KVA1 (de novo sequence locus 4025)

Drosophila melanogaster xylosyltransferase (oxt)

Yes

2c

F6

Q9VAF0 (de novo sequence locus 4149)

Drosophila melanogaster zinc transporter ZIP13 homolog (Zip99C)

Yes

2c

  1. aThe F2 antigen could not be produced in E. coli and was not included in the vaccination trial
  2. bIdentified after searching MS/MS raw files against the Neoptera Uniprot database
  3. cIdentified by PIT using a database created from transcriptomics data of predicted transmembrane and secreted proteins