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Table 4 Genotyping results of the voltage-gated sodium channel gene at 1534 codon and association with resistance to DDT in five Aedes albopictus populations in Guangzhou, China. The significance threshold is P < 0.01 after Bonferroni correction for multiple testing

From: Evidence for multiple-insecticide resistance in urban Aedes albopictus populations in southern China

Area

Population

Phenotype

n

Genotype

Odds ratio (95% CI)

P–value of Fisher’s exact probability test

FF

FS

SS

FL

LL

LS

F1534S

F1534 L

F1534S

F1534 L

Urban

UBT

R

28

2

11

12

1

0

2

1.9 (0.94–3.96)

1.9 (0.38–9.34)

0.052

0.353

S

46

15

9

18

1

0

3

    

UYS

R

39

5

9

7

6

1

11

2.3 (1.19–4.59)

2.2 (1.00–4.86)

0.010

0.040

S

52

13

19

3

10

1

7

    

Suburban

SBL

R

10

3

6

1

0

0

0

0.9 (0.31–2.51)

na

0.519

0.542

S

29

11

9

7

1

0

1

    

SPX

R

10

0

1

8

0

0

1

4.2 (0.50–34.24)

2.0 (0.11–37.83)

0.143

0.589

S

35

5

2

22

0

0

6

    

Rural

RCD

R

13

8

3

2

0

0

0

1.0 (0.37–2.72)

na

0.587

0.346

S

43

22

16

1

0

0

4

    
  1. Abbreviations: F wildtype F1534 allele, S F1534S allele, L F1534 L, R resistant, S susceptible, na not applicable, FF homozygous phenylalanine/phenylalanine, FS heterozygotes phenylalanine/ leucine, SS homozygous serine/serine, FL heterozygotes phenylalanine/ leucine, LL homozygous leucine/ leucine, SL heterozygotes serine/leucine