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Table 5 Dirofilaria immitis microfilaria uptake by Aedes aegypti mosquitoes blood-fed on infected dogs untreated or topically treated with DPP on Day 0

From: Blocking the transmission of heartworm (Dirofilaria immitis) to mosquitoes (Aedes aegypti) by weekly exposure for one month to microfilaremic dogs treated once topically with dinotefuran-permethrin-pyriproxyfen

Control

DPPa

Day

Fed Mosquitoes

Dissected/Totalb

Microfilariae/ Mosquitoc

Fed Mosquitoes Dissected/ Total

Microfilariae/ Mosquito

−7

60/208

57.5 ± 83.4

(0-416)

60/180

153.1 ± 218.8

(0-742)

7

60/206

98.6 ± 81.0

(7-316)

0/0

0

14

60/224

155.5 ± 109.8

(15-650)

Nad/6

21

60/177

96.0 ± 59.4

(5-258)

Na/8

28

60/203

191.1 ± 120.4

(10-638)

Na/8

  1. aDPP: dinotefuran + permethrin + pyriproxyfen (Vectra® 3D)
  2. bFed mosquitoes sampled from three exposure cages (20 per dog) during exposure for dissection and microfilarial count /total fed mosquitoes count
  3. cAverage number ± standard deviation (min-max) of microfilariae per mosquito dissected
  4. dFed mosquitoes were not dissected and were incubated for survival assessment