Blocking the transmission of heartworm (Dirofilaria immitis) to mosquitoes (Aedes aegypti) by weekly exposure for one month to microfilaremic dogs treated once topically with dinotefuran-permethrin-pyriproxyfen

Table 1 Study design

Study Step	Study Day
Treatment administration	0
Microfilaremia	−7	m^a	14	21	28
Mosquito infestation	−7	7	14	21	28
MF^b count in mosquito midguts	−7	7	14	21	28
Incubation of mosquitoes	−6-9	8-23	15-30	22-37	29-44
L3 count in mosquitoes	9	23	30	37	44

ISSN: 1756-3305