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Table 3 Assessment of skin lesions using a flea bite hypersensitivity severity scale for dogs naturally infested with fleas and administered either Sarolaner or Spinosad oral treatments

From: Evaluation of sarolaner and spinosad oral treatments to eliminate fleas, reduce dermatologic lesions and minimize pruritus in naturally infested dogs in west Central Florida, USA

Treatment group

 

Days post-treatmenta

Day 0

Day 30

Day 60

Sarolanerb

# Dogs

29

29

28

Mean FAD Scoree

11.00

5.38

3.71

SD

8.19

4.97

4.03

Range

1–30

0–21

0–15

Reduction (%)e

 

51.10

66.23

Spinosadc

# Dogs

26

26

25

Mean FAD Scored

13.62

6.73

5.16

SD

7.42

6.51

5.17

Range

3–32

0–26

0–24

Reduction (%)

 

50.56

62.10

  1. Abbreviation: SD standard deviation
  2. aIn both groups, dogs were treated on day 0 and once between days 28 – 30
  3. bDogs were orally administered Sarolaner chewables (Simparica® Zoetis) according to label directions
  4. cDogs were orally administered Spinosad flavored tablets (Comfortis® Elanco) according to label directions
  5. dArithmetic mean Flea Allergy Dermatitis lesion score [33]
  6. e{(Day 0 arithmetic mean FAD score – day x arithmetic mean FAD score)/day 0 arithmetic mean FAD score)} × 100
  7. No significant differences between the two groups were observed, for any day, based on the repeated measures analysis (P = 0.2086)