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Table 1 On-animal flea counts in naturally infested homes when dogs were administered either Sarolaner or Spinosad oral treatments

From: Evaluation of sarolaner and spinosad oral treatments to eliminate fleas, reduce dermatologic lesions and minimize pruritus in naturally infested dogs in west Central Florida, USA

Treatment group

No. of dogs on day 0

 

Days post-treatmenta

Day 0

Day 7

Day 14

Day 21

Day 28–30

Day 40-45

Day 56-60

Sarolanerb

29

Geomeand

24.12

0.24

0.20

0.07

0.07

0.00

0.02

Range

5–19

0–1

0–2

0–3

0–1

0–0

0–1

% controle

 

99.00

99.18

99.69

99.69

100

99.90

%

0

68.97

75.86

93.10

89.66

100

96.43

(#) dogs with no fleas

(0/29)

(20/29)

(22/29)

(27/29)

(26/29)

(29/29)

(27/28)

Spinosadc

26

Geomean

25.71

0.60

0.21

0.19

0.17

0.08

0.06

Range

7–128

0–6

0–8

0–3

0–6

0–1

0–1

% control

 

97.26

99.20

99.25

99.35

99.68

99.78

%

0.0

61.54

84.62

80.77

84.62

88.46

92.0

(#) dogs with no fleas

(0/26)

(16/26)

(22/26)

(21/26)

(22/26)

(23/26)

(23/25)

  1. aIn both groups, dogs were treated on day 0 and once between days 28–30
  2. bDogs were orally administered Sarolaner chewables (Simparica® Zoetis) according to label directions
  3. cDogs were orally administered Spinosad flavored tablets (Comfortis® Elanco) according to label directions
  4. dGeometric mean numbers of fleas in visual area counts on pets
  5. e{(Day 0 geometric mean animal area flea counts – day x geometric mean animal area flea counts) / day 0 geometric mean animal area flea counts)} × 100
  6. No significant differences between the two groups were observed, for any day, based on the repeated measures analysis (P = 0.1969)
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