Fig. 1

Late-phase immunity is intact in both control and TEP1 mutant lines. Oocyst numbers in the midgut were determined in control-X1 and TEP1 mutant lines at 2 and 8 days post- P. berghei infection. Oocyst survival in both control-X1 (a) and TEP1 mutant (b) lines is reduced between day 2 and day 8 as measure by oocyst numbers. For both experiments, each dot represents the number of oocysts on an individual midgut. Oocyst numbers were pooled from three independent experiments, with the median indicated by the horizontal red line. Oocyst numbers were analyzed using a Mann-Whitney test. Asterisks denote significance (****P < 0.0001)