Table 5 Proteins involved in lipid metabolism and transport identified in the midgut of Ornithodoros moubata females before feeding (unfed) and at 48 h post-feeding (fed). (T) Gene identified in the intestinal transcriptome of O. moubata [29]

Unfed

mRNA_Om

A0A087U096

Group XV phospholipase A2 (T)

0.14

–

Phospholipase activity

Unfed

mRNA_Om

B7PP53

Triacylglycerol lipase (T)

0.05

–

Lipase activity

Unfed

EST_Acari

B7PV61

Erlin-2

0.31

–

Cholesterol binding

Fed

mRNA_Om

B7Q350

Niemann-Pick type C1 domain-containing protein (T)

–

0.07

Cholesterol transporter activity

Fed

mRNA_Om

Q6QVL7

NPC1 (T)

–

0.33

Cholesterol transporter activity

Fed

mRNA_Om

B7Q6Z1

Saposin (T)

–

0.08

Enzyme activator activity

Fed

mRNA_Om

G9M4L6

Vitellogenin-B (T)

–

0.57

Lipid transporter activity

Unfed-Fed

EST_Acari

E2C1X2

Ankyrin-2 (T)

1.82

0.43

Lipid binding

Unfed-Fed

mRNA_Om

B7QMW0

Fatty acid-binding protein FABP (T)

8.66

0.49

Lipid transporter activity

Unfed-Fed

mRNA_Om

B7PK21

Glucosylceramidase (T)

1.01

0.62

Glucosylceramidase activity

Unfed-Fed

mRNA_Om

B7PG19

Inositol-1-phosphate synthetase (T)

0.07

0.04

Isomerase activity

Unfed-Fed

mRNA_Om

B7PJA8

Long chain fatty acid CoA ligase (T)

1.61

1.55

Ligase activity

Unfed-Fed

mRNA_Om

B7QDC5

Low-density lipoprotein receptor, putative (T)

3.71

0.17

Hydrolase activity

Unfed-Fed

mRNA_Om

B7P1A9

Major epididymal secretory protein HE1 (T)

3.43

0.86

Cholesterol transporter activity

Unfed-Fed

mRNA_Om

B7Q8J7

N-acylsphingosine amidohydrolase (Acid ceramidase) (T)

1.43

0.71

Ceramidase activity

Unfed-Fed

mRNA_Om

B7Q381

Putative uncharacterized protein (T)

0.24

0.24

Transporter activity

Unfed-Fed

mRNA_Om

B7PYU9

Rat sphingolipid delta 4 desaturase (T)

0.06

0.09

Oxidoreductase activity

Unfed-Fed

mRNA_Om

B6ZIV7

Vitellogenin (T)

1.65

0.57

Lipid transporter activity

Unfed-Fed

mRNA_Om

E1CAX9

Vitellogenin-1 (T)

13.21

0.33

Lipid transporter activity