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Fig. 4 | Parasites & Vectors

Fig. 4

From: Vaccination of rabbits with immunodominant antigens from Sarcoptes scabiei induced high levels of humoral responses and pro-inflammatory cytokines but confers limited protection

Fig. 4

Variation of circulating serum S. scabiei-specific IgE (a) and total IgG (b) antibody levels in sera of immunised rabbits detected by ELISA (Casais et al., 2015). Rabbits were immunised four times (1st, 2nd, 3rd and 4th doses); control refers to the group vaccinated with PBS and Quil A adjuvant and recAgs refers to the group immunised with a mixture of two S. scabiei recombinant antigens (Ssλ20∆B3 and GST-Ssλ15) and Quil A. The dashed line represents the cut-off level of the ELISA used to determine the IgG levels (0.03 relative OD450 nm). Data points correspond to the mean values, and the error bars represent the standard error. The IgG levels in the recAgs immunised group were significantly higher than in the control (F (1,14) = 52.31, P < 0.0001), while IgE levels were not significantly different between both groups (F (1,10) = 0.406, P = 0.538)

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