| Non-treated controlsd,g
| Imidacloprid/flumethrine,g
| Fipronil/(s)-methoprenef,g
|
---|
Study day | Mean No. of fleas | Mean No. of fleas | % controlh
Geomeans | Mean No. of fleas | % controlh
Geomeans |
---|
2 | 55.0a (55.8) | 0 (0) | 100b
| 0.1 (0.1) | 99.9b
|
8 | 55.3a (57.9) | 0 (0) | 100b
| 0.6 (1.0) | 98.8b
|
15 | 52.0a (53.5) | 0.9 (1.4) | 98.3b
| 0.4 (0.7) | 99.1b
|
30 | 47.0a (48.7) | 0 (0) | 100b
| 0.2 (0.4) | 99.5b
|
60 | 35.7a (36.6) | 0 (0) | 100b
| 1.0 (2.5) | 97.2b
|
90 | 40.4a (42.4) | 0 (0) | 100b
| 12.8 (15.7) | 68.2c
|
120 | 38.8a (39.6) | 0.1 (0.1) | 99.8b
| 1.9 (4.0) | 95.0b
|
150 | 45.9a (47.3) | 0 (0) | 100b
| 7.1 (10.4) | 84.5c
|
180 | 38.3a (40.2) | 0 (0) | 100b
| 1.5 (2.6) | 96.1b
|
210 | 46.8a (47.3) | 0.1 (0.1) | 99.8b
| 12.5 (14.0) | 73.3c
|
240 | 48.5a (50.9) | 0.9 (1.4) | 98.2b
| 3.3 (4.1) | 93.2b
|
-
d Each of 10 cats in the control group received no treatment
-
e Each of 10 cats in the imidacloprid/flumethrin group were fitted with a Seresto® collar (Bayer Animal Health) on day 0. Note that two cats were removed from this group (one on study day 2 and one on study day 10)
-
f Each of ten cats in the fipronil/(s)-methoprene group were treated Frontline® Plus for Cats and Kittens (Merial) on day 0 and then monthly through day 210
-
g Each cat was infested with 100 adult C. f. felis on days 0, 7, 14, 29, 59, 89, 119, 149, 179, 209, and 239
-
h % efficacy/Control = (GM flea count (control) – GM flea count (treatment) × 100)/GM flea count (control) \( \%\kern0.5em \mathrm{Control}=\frac{\mathrm{geometric}\;\mathrm{mean}\;\mathrm{count}\ \mathrm{control}\hbox{-} \mathrm{geometric}\ \mathrm{mean}\ \mathrm{count}\ \mathrm{treatment}}{\mathrm{geometric}\ \mathrm{mean}\ \mathrm{count}\ \mathrm{treatment}}\times 100 \)
-
a,b,c Values across rows with unlike superscripts are significantly different (P < 0.0001)