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Table 3 Demographic and clinical characteristics of dogs infected with Borrelia persica included in the study

From: Borrelia persica infection in dogs and cats: clinical manifestations, clinicopathological findings and genetic characterization

Dog number (sample ID)

1 (61887)

2 (8726)

3 (4663)

4 (9835)

5 (8692)

Location

Yavne' el

Meitar

Hashmonaim

Karmei Yosef

Amatzia

Year of diagnosis

2003

2012

2012

2013

2015

Sex; age in years

M; 1.5

F; 3

M; 4

F; 12.5

M; 2.5

Breed

Siberian Husky

Mixed breed

Labrador

Mixed breed

German Shepherd

Fever

40.8 ° C

41.2 °C

39.5 °C

–; (38.9 ° C)

39.4 °C

Lethargy

+

+

+

+

+

Anorexia

+

+

+

+

+

Pale mucous membranes

+

+

+

-

Icterus

+

-

Anemia

+

+

+

+

-

Hematocrit L/L

0.271

0.340

0.189

0.270

0.375

MCV fL

75.3

77.7

66.7

69.2

67.5

MCHC g/l

305

305

337

353

381

Leukocytosis

-

WBC number × 109/l

10.69

11.80

12.80

9.13

7.70

Thrombocytopenia

+

+

+

PLT number × 109/l

168

41

171

86

39

Co-infection:

     

PCR for E. canis

-

PCR for Babesia sp.

+

+

+

-

Antibiotic treatment

ciprofloxacin for 2 days and then doxycycline

doxycycline

long acting tetracycline and amoxicillin/clavulanic acid

amoxicillin initially, continued with doxycycline

doxycycline

Survival and response to treatment

survived; no spirochetemia at recheck 7 days after treatment initiation

survived; no spirochetemia at recheck 11 days after treatment initiation; treated also with imidocarb dipropionate for babesiosis

died one day after treatment initiation

survived; improved a day after initial treatment with amoxicillin; treated also with imidocarb dipropionate for babesiosis

survived; recovered clinically at recheck 4 days after treatment initiation

  1. Hematocrit, reference range 0.371–0.57 L/L; MCV mean cell volume, range 58.8–71.2 fL; MCHC mean corpuscular hemoglobin concentration, range 310–362 g/l; WBC white blood cells, range 5.2–13.9 × 109/L; PLT: platelets, range 150–400 × 109/l