Fig. 6From: Disrupted ADP-ribose metabolism with nuclear Poly (ADP-ribose) accumulation leads to different cell death pathways in presence of hydrogen peroxide in procyclic Trypanosoma brucei Cell death analysis by flow cytometry. a The diagram represents cell subpopulations identified by staining with propidium iodide (PI) and Annexin V-FITC conjugate. b Wild type culture was treated with 10 μg/mL of Concanavalin A (Con A) as an apoptosis-like control. c Diagram of wild type (WT), TbPARP over-expressing (p2216-TbPARP) and TbPARG down-regulated (p2T7-TbPARG) procyclic cultures after 1 mM H2O2 treatment for different time intervals. Transgenic parasites were previously induced for three daysBack to article page