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Fig. 1 | Parasites & Vectors

Fig. 1

From: Schistosoma japonicum HSP60-derived peptide SJMHE1 suppresses delayed-type hypersensitivity in a murine model

Fig. 1

Suppression of DTH responses by SJMHE1. a BALB/c mice were sensitised with OVA alone or combined with various amounts of SJMHE1 (as indicated). Challenge with OVA occurred 7 days later, and the DTH responses were assessed over the subsequent 24 h with the change in ear thickness. The DTH responses are expressed as the mean ± SD of 12 mice from two independent experiments; b BALB/c mice were sensitised with OVA alone or combined with 30 μg of SJMHE1. Challenge with OVA occurred 7 days later; 24 h after the challenge, the ear was removed and homogenised. Cytokine levels in the supernatants were measured from the homogenised tissue. Data are shown as the mean ± SD of 12 mice from two independent experiments. Asterisks indicate significant differences analysed using Student’s t-test (*P < 0.05; **P < 0.01; ***P < 0.001)

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