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Table 2 Sensitivity analyses of model projections to changes in the values of key parameters. The numerical values record the percentage reduction in the predicted mean intensity of infection in each age group from a rising treatment coverage to 75 %, and to 27.4 % in adults, in 2020 as compared to baseline in 2003

From: What is required in terms of mass drug administration to interrupt the transmission of schistosome parasites in regions of endemic infection?

Parameter

Pre-SAC mean burden

SAC mean burden

Adults mean burden

Overall population mean burden

Fitted parameter values (Table 1)

73 %

91 %

84 %

86 %

Higher and lower transmission setting (R0 + 1.0, −0.25)

49 %, 81 %

78 %, 94 %

76 %, 86 %

76 %, 90 %

Coverage level achieved in 2020 (60 %, 90 %)

77 %, 67 %

94 %, 85 %

87 %, 79 %

90 %, 81 %

Degree of exposure and contribution of children to the infectious reservoir (5–16 years) (β2 and β2 + 50 %, −50 %)

73 %, 71 %

91 %, 90 %

84 %, 82 %

87 %, 85 %