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Table 2 Sensitivity analyses of model projections to changes in the values of key parameters

From: What impact will the achievement of the current World Health Organisation targets for anthelmintic treatment coverage in children have on the intensity of soil transmitted helminth infections?

 

Pre-SAC

SAC

Adults

Overall population

Ascaris

    

 Fitted parameters (see Table 1)

71

75

63

70

 Higher and lower transmission setting (R0 + 1.0, −0.5)

35, 99

45, 99

24, 99

36, 99

 Coverage level achieved in 2020 (60 %, 90 %)

59, 82

64, 85

51, 73

58,80

 The degree of exposure and contribution of Pre-SAC and SAC to the infectious reservoir (β2 and β3 + 50 %, −50 %)

83, 48

85, 56

76, 37

82, 45

Trichuris

    

 Fitted parameters (see Table 1)

43

48

40

44

 Higher and lower transmission setting (R0 + 1.0, −0.5)

24, 80

31, 81

20, 77

24, 79

 Coverage level achieved in 2020 (60 %, 90 %)

37, 49

42, 54

34, 45

38, 49

 The degree of exposure and contribution of Pre-SAC and SAC to the infectious reservoir (β2 and β3 + 50 %, −50 %)

45, 38

50, 43

43, 32

46, 37

Hookworm

    

 Fitted parameters (see Table 1)

39

50

16

22

 Higher and lower transmission setting (R0 + 1.0, −0.5)

36, 43

48, 54

12, 21

19, 27

 Coverage level achieved in 2020 (60 %, 90 %)

34, 43

45, 55

14, 17

20, 24

 The degree of exposure and contribution of Pre-SAC and SAC to the infectious reservoir (β2 and β3 + 50 %, −50 %)

45, 33

55, 45

24, 6

32, 10

  1. The numerical values record the percentage reduction in the predicted mean intensity of infection in each age group from a rising treatment coverage to 75 % in 2020 as compared to baseline in 2003. The default parameters are in Table 1