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Table 5 Model-predicted required mean number of years of mass treatments for different intervention scenarios for achieving the successful interruption of LF transmission in each of the study sites investigated. The required years of mass treatments were determined by evaluating whether as a result of intervention, the model-predicted community-level mf prevalence had reduced below the mf elimination threshold signifying 95 % probability of elimination for the four scenarios: 1) intervention by annual mass drug administration (MDA) alone; 2) annual MDA with supplemental vector control (VC); 3) biennial MDA alone; and 4) biennial MDA with supplemental VC. VC, where applicable, was implemented at the community coverage of 80 %. The results in this table are shown for three MDA coverages: 60, 80 and 100 %

From: Bayesian calibration of simulation models for supporting management of the elimination of the macroparasitic disease, Lymphatic Filariasis

 

Annual MDA alone

Annual MDA + VC

Biennial MDA alone

Biennial MDA + VC

Study villages

60 %

a80%

100 %

60 %

a80%

100 %

60 %

a80%

100 %

60 %

a80%

100 %

Peneng

17

12

9

10

7

6

9

6

5

5

4

3

Albulum

26

20

15

17

12

9

15

11

10

9

7

6

Yauatong

28

23

18

19

14

11

18

14

13

10

8

7

Nanaha

15

10

8

8

6

4

8

5

5

4

3

2

Ngahmbule

15

10

8

9

7

5

8

5

4

5

3

2

Tawalani

18

13

10

9

7

5

10

7

4

5

3

1

Jaribuni

17

13

9

8

6

4

9

6

4

4

2

1

Tringela

20

14

11

10

8

6

11

7

4

5

3

1

Chiconi

22

16

13

12

9

7

12

9

5

6

4

2

Masaika

18

13

10

10

8

6

10

7

4

5

3

1

Kirare

21

16

12

8

6

4

12

8

4

4

2

1

Alebtong

25

19

14

12

9

7

15

10

6

7

4

2

Lwala

20

14

11

9

7

5

11

8

4

5

3

1

Obalanga

22

16

13

7

5

4

13

9

5

3

2

1

Kingwede

16

11

8

10

8

6

8

6

3

5

3

1

Mao

21

16

12

11

8

6

12

8

5

6

4

1

Mambrui

17

12

9

8

6

4

9

6

4

4

2

1

Pakistan

15

10

8

8

6

4

8

5

5

4

3

2

Pondicherry

24

18

13

15

11

8

13

9

8

8

6

5

Calcutta

15

11

8

9

7

5

8

5

4

5

3

2

Vettavallam

19

13

10

11

8

6

10

7

6

6

4

3

Jakarta

25

21

16

17

13

9

16

12

9

9

6

5

bTotal variance(An)

 

3.52

  

2.66

  

1.37

  

1.15

 

bTotal variance(Cx)

 

1.52

  

1.20

  

0.51

  

0.49

 
  1. aThe required years of mass treatments at the MDA coverage of 80 %, without and with vector control, significantly differed within Anopheline and Culicine settings (Kruskal-Wallis test p-values <0.0001)
  2. bTotal variance denotes the overall variance in the required years of mass treatments estimated from all sites within each of the Anopheline and Culicine settings. Data are provided for 80 % coverage for annual and biennial MDAs without and with vector control at 80 % coverage