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Fig. 2 | Parasites & Vectors

Fig. 2

From: Quantitative evaluation of the strategy to eliminate human African trypanosomiasis in the Democratic Republic of Congo

Fig. 2

Multi-host model of HAT with various host groups able to acquire and transmit HAT infection (humans and reservoir animals), further non-reservoir animal species (others) and tsetse. Human hosts follow the progression which includes an infectious stage 1 disease, I H1, infectious stage 2 disease , I H2, and a non-infectious (due to hospitalisation) disease, R H . Unfed tsetse are susceptible, S V , and following a blood-meal become either exposed, E V , or have reduce susceptibility to the trypanosomes , G V . Tsetse select their blood-meal from one of the host species. Any blood-meals taken upon non-reservoir hosts do not result in infection. The transmission of infection between humans/tsetse and reservoirs/tsetse is shown by grey paths. Additional humans follow the same progression as the first human type but may receive more bites (high-risk) or may not participate in screening. Transmission from additional humans to tsetse is not shown here but occurs in the same way as humans to tsetse

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Parasites & Vectors

ISSN: 1756-3305

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