Fig. 5
From: Tick sialostatins L and L2 differentially influence dendritic cell responses to Borrelia spirochetes
Maturation of plasmacytoid dendritic cells induced by Borrelia, TLR-7, and TLR-9 ligation in the presence of sialostatins. Plasmacytoid dendritic cells were activated with Borrelia at MOI = 10 (a), imiquimod (2 μg/ml) (b), or CpG (50 nM) (c) in the presence or absence of sialostatins (both 3 μM). The expression of costimulatory molecule CD86 was analysed by flow cytometry among CD11c+, CD11b-, and B220+ cell population. Medium fluorescence intensity (MFI) is shown. The phenotype of plasmacytoid DC from CD11c population is shown (d)