Group 1 (Normal) | Normal control/ Naïve mice (Administered PBS only) |
Group 2 (INF) | Infected control (BALB/c mice infected with L. donovani promastigotes and administered PBS) |
Group 3 (VC) | Vehicle control (0.5% DMSO in PBS, the highest concentration used to dissolve the fractions/compounds) |
Group 4 (AmB) | Amphotericin B administered intravenously (i.v.) at (5Â mg/kg bw) |
Group 5 (ALE100) | ALE administered intraperitoneally (i.p.) at 100Â mg/kg bw |
Group 6 (ALE 200) | ALE administered i.p. at 200Â mg/kg bw |
Group 7 (ASE100) | ASE administered i.p. at 100Â mg/kg bw |
Group 8 (ASE200) | ASE administered i.p. at 200Â mg/kg bw |