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Table 2 Classification according to likelihood of the diagnosis, and proportion of diagnoses within the targeted period, of validated general practitioner (GP) reported cases of disseminated Lyme borreliosis* and persisting symptoms attributed to Lyme borreliosis**

From: Physician reported incidence of early and late Lyme borreliosis

Likelihood of diagnoses for disseminated Lyme borreliosis*

(n/N)

Percentage (95%CI)

Criteria for classification

  

Very likely diagnosis

(527/590)

89.3% (86.5%-91.6%)

- Diagnosed by a medical specialist.

  

OR

- Diagnosis based on clinical symptoms, laboratory diagnosis and anamnesis.

Likely diagnosis

(27/590)

4.6% (3.1%-6.7%)

- Diagnosis based on clinical symptoms and anamnesis.

  

OR

- Diagnosis based on laboratory diagnosis and anamnesis.

Possible diagnosis

(22/590)

3.7% (2.4%-5.7%)

- Diagnosis not made by medical specialist.

  

- Diagnosis not based on clinical symptoms, laboratory diagnosis and anamnesis.

- Diagnosis not based on clinical symptoms and anamnesis.

- Diagnosis not based on laboratory diagnosis and anamnesis.

OR

- GP reports that the diagnosis is uncertain.

OR

- Patient proposed diagnosis Lyme borreliosis, but GP or medical specialist disagree.

- Diagnosed by an alternative healer.

Invalid report

(14/590)

2.4% (1.4%-4.1%)

- GP declared to have erroneously marked the Lyme borreliosis case on the questionnaire.

  

- The diagnosis Lyme borreliosis was abandoned after further specific diagnostics.

Diagnosed within targeted period

(89/141)

63.1% (54.6%-70.9%)

2009 or 2010

Likelihood of diagnoses for persisting symptoms attributed to lyme borreliosis**

(n/N)

Percentage (95%CI)

Criteria for classification

  

Likely diagnosis

(414/544)

76.1% (72.2%-79.6%)

- Diagnosed by a medical specialist.

OR

  

- Diagnosis based on clinical symptoms, laboratory diagnosis and anamnesis.

Possible diagnosis

(106/544)

19.5% (16.3%-23.1%)

- Diagnosis based on clinical symptoms and anamnesis.

OR

- Diagnosis based on laboratory diagnosis and anamnesis.

OR

- GP reports that the diagnosis is uncertain.

OR

- GP reports that the diagnosis is uncertain.

- Patient proposed diagnosis Lyme borreliosis, but GP or medical specialist disagree.

- Diagnosed by an alternative healer.

Invalid Report

(24/544)

4.4% (2.9%-6.6%)

- GP declared to have erroneously marked the Lyme borreliosis case on the questionnaire.

- The diagnosis Lyme borreliosis was abandoned after further specific diagnostics.

Diagnosed within targeted period

(41/78)

52.6% (41.0%-63.9%)

2008 or 2010

  1. 95%CI, 95% confidence interval.
  2. *“Disseminated Lyme borreliosis” includes: borrelial lymphocytoma, acrodermatitis chronica atrophicans, Lyme neuroborreliosis, Lyme arthritis, Lyme carditis, ocular manifestations.
  3. **“Persisting symptoms attributed to Lyme borreliosis” includes: encephalopathy, persisting symptoms after treatment for Lyme borreliosis with or without active Borrelia infection.