Skip to main content

Table 2 The spleeno-somatic and hepato-somatic indices of BALB/c infected with L. major , S. mansoni and those co-infected with L. major + S. mansoni undergoing various treatments with Pentostam and PZQ between week 8 and week 10

From: Combination therapy using Pentostam and Praziquantel improves lesion healing and parasite resolution in BALB/c mice co-infected with Leishmania major and Schistosoma mansoni

Infection

Drug administration

Spleeno-somatic index

Hepato-somatic index

L. major

 

Week 8

Week 10

Week 8

Week 10

 

P

0.77 ± 0.031

0.74 ± 0.039

4.45 ± 0.14

3.92 ± 0.08

 

PZQ

1.11 ± 0.173

1.45 ± 0.100

4.67 ± 0.15

5.18 ± 0.23

 

P + PZQ

0.81 ± 0.016

0.74 ± 0.029

4.25 ± 0.18

3.81 ± 0.13

 

PBS

1.03 ± 0.150

1.67 ± 0.084

4.57 ± 0.10

5.97 ± 0.32

S. mansoni

P

1.11 ± 0.088

1.49 ± 0.066

8.83 ± 1.11

10.19 ± 0.50

 

PZQ

0.94 ± 0.073

0.96 ± 0.064

4.61 ± 0.09

4.14 ± 0.21

 

P + PZQ

0.86 ± 0.081

0.79 ± 0.044

4.46 ± 0.07

4.04 ± 0.22

 

PBS

1.09 ± 0.081

1.72 ± 0.073

5.87 ± 1.12

7.66 ± 0.27

L. major+

P

1.11 ± 0.165

1.37 ± 0.076

7.83 ± 1.44

8.68 ± 2.04

S. mansoni

PZQ

1.20 ± 0.111

1.41 ± 0.077

8.64 ± 0.12

9.47 ± 0.13

 

P + PZQ

1.03 ± 0.075

1.01 ± 0.041

4.46 ± 0.11

4.19 ± 0.07

 

PBS

1.17 ± 0.046

1.88 ± 0.051

5.81 ± 0.16

7.50 ± 0.43